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1

Croton megalobotrys Müll Arg. and Vitex doniana (Sweet): Traditional medicinal plants in a three-step treatment regimen that inhibit in vitro replication of HIV-1

Tietjen, Ian, Gatonye, Teresia, Ngwenya, Barbara N., Namushe, Amos, Simonambanga, Sundana, Muzila, Mbaki, Mwimanzi, Philip, Xiao, Jianbo, Fedida, David, Brumme, Zabrina L., Brockman, Mark A., Andrae-M

Journal:

Journal of Ethnopharmacology

Year:

2016

Language:

english

File:

PDF, 1.58 MB

english, 2016

2

Research into the therapeutic roles of two-pore-domain potassium channels

Zeineb Es-Salah-Lamoureux, David F. Steele, David Fedida

Journal:

Trends in Pharmacological Sciences

Year:

2010

Language:

english

File:

PDF, 24.22 MB

english, 2010

3

Immune Memory to Sudan Virus: Comparison between Two Separate Disease Outbreaks

Sobarzo, Ariel, Eskira, Yael, Herbert, Andrew, Kuehne, Ana, Stonier, Spencer, Ochayon, David, Fedida-Metula, Shlomit, Balinandi, Steven, Kislev, Yaara, Tali, Neta, Lewis, Eli, Lutwama, Julius, Dye, Jo

Journal:

Year:

2015

Language:

english

File:

PDF, 1.49 MB

english, 2015

4

Évaluation prospective d’une cohorte de 81 patients pris en charge pour une fracture de l’extrémité distale du radius par plaque antérieure verrouillée

Krief, Elie, Lippmann, Stenley, Maes-clavier, Clavier, David, Emmanuel, Mertl, Patrice, Appy-fedida, Benjamin

Journal:

Chirurgie de la Main

Year:

2015

Language:

french

File:

PDF, 217 KB

french, 2015

5

Probing the molecular basis of hERG drug block with unnatural amino acids

Macdonald, Logan C., Kim, Robin Y., Kurata, Harley T., Fedida, David

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 3.26 MB

english, 2018

6

Correspondence of Neutralizing Humoral Immunity and CD4 T Cell Responses in Long Recovered Sudan Virus Survivors

Sobarzo, Ariel, Stonier, Spencer, Herbert, Andrew, Ochayon, David, Kuehne, Ana, Eskira, Yael, Fedida-Metula, Shlomit, Tali, Neta, Lewis, Eli, Egesa, Moses, Cose, Stephen, Lutwama, Julius, Yavelsky, Vi

Journal:

Year:

2016

Language:

english

File:

PDF, 1.47 MB

english, 2016

7

Hormonal Signaling Actions on Kv7.1 (KCNQ1) Channels

Thompson, Emely, Eldstrom, Jodene, Fedida, David

Journal:

Annual Review of Pharmacology

Year:

2021

File:

PDF, 811 KB

2021

8

Better antiarrhythmics? Development of antiarrhythmic drugs selective for ischaemia-dependent arrhythmias

Allen I. Bain, Terrance D. Barrett, Gregory N. Beatch, David Fedida, Eric S. Hayes, Bertrand Plouvier, Michael K. Pugsley, Michael J.A. Walker, Mariah L. Walker, Richard A. Wall, Sandro L. Yong, Alexa

Journal:

Drug Development Research

Year:

1997

Language:

english

File:

PDF, 287 KB

english, 1997

9

Structure-Based Virtual Screening and Electrophysiological Evaluation of New Chemotypes of Kv1.5 Channel Blockers

Qian Yang, David Fedida, Hongjian Xu, Binghe Wang, Lupei Du, Xiaojian Wang, Minyong Li, Qidong You

Journal:

Year:

2010

Language:

english

File:

PDF, 492 KB

english, 2010

10

Block by internal Mg2+causes voltage-dependent inactivation of Kv1.5

Thomas W. Claydon, Daniel C. H. Kwan, David Fedida, Steven J. Kehl

Journal:

European Biophysics Journal

Year:

2006

Language:

english

File:

PDF, 444 KB

english, 2006

11

Modeling of high-affinity binding of the novel atrial anti-arrhythmic agent, vernakalant, to Kv1.5 channels

Jodene Eldstrom, David Fedida

Journal:

Journal of Molecular Graphics and Modelling

Year:

2009

Language:

english

File:

PDF, 833 KB

english, 2009

12

Modulation of slow inactivation in human cardiac Kv1.5 channels by extra- and intracellular permeant cations

David Fedida, Neil D. Maruoka, Shunping Lin

Journal:

The Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 764 KB

english, 1999

13

Gating current studies reveal both intra- and extracellular cation modulation of K+ channel deactivation

Zhuren Wang, Xue Zhang, David Fedida

Journal:

The Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 473 KB

english, 1999

14

Regulation of transient Na+ conductance by intra- and extracellular K+ in the human delayed rectifier K+ channel Kv1.5

Zhuren Wang, Xue Zhang, David Fedida

Journal:

The Journal of Physiology

Year:

2000

Language:

english

File:

PDF, 368 KB

english, 2000

15

Modulation of human ether-à-go-go-related K+ (HERG) channel inactivation by Cs+ and K+

Shetuan Zhang, Steven J. Kehl, David Fedida

Journal:

The Journal of Physiology

Year:

2003

Language:

english

File:

PDF, 356 KB

english, 2003

16

The Mechanism of Atrial Antiarrhythmic Action of RSD1235

DAVID FEDIDA, PETER M.R. ORTH, JANET Y.C. CHEN, SHUNPING LIN, BERTRAND PLOUVIER, GRACE JUNG, ALAN M. EZRIN, GREGORY N. BEATCH

Journal:

Journal of Cardiovascular Electrophysiology

Year:

2005

Language:

english

File:

PDF, 342 KB

english, 2005

17

The Role of Late INa and Antiarrhythmic Drugs in EAD Formation and Termination in Purkinje Fibers

DAVID FEDIDA, PETER M.R. ORTH, J. CHRISTIAN HESKETH, ALAN M. EZRIN

Journal:

Journal of Cardiovascular Electrophysiology

Year:

2006

Language:

english

File:

PDF, 375 KB

english, 2006

18

Non-specific action of methoxamine on Ito, and the cloned channels hKv 1.5 and Kv 4.2

Chris Parker, Qi Li, David Fedida

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 432 KB

english, 1999

19

Molecular determinants of the inhibition of human Kv1.5 potassium currents by external protons and Zn2+

Steven J. Kehl, Cyrus Eduljee, Daniel C. H. Kwan, Shetuan Zhang, David Fedida

Journal:

The Journal of Physiology

Year:

2002

Language:

english

File:

PDF, 657 KB

english, 2002

20

Heterogeneous expression of repolarizing, voltage-gated K+ currents in adult mouse ventricles

Sylvain Brunet, Franck Aimond, Huilin Li, Weinong Guo, Jodene Eldstrom, David Fedida, Kathryn A. Yamada, Jeanne M. Nerbonne

Journal:

The Journal of Physiology

Year:

2004

Language:

english

File:

PDF, 471 KB

english, 2004

21

Separation of P/C- and U-type inactivation pathways in Kv1.5 potassium channels

Harley T. Kurata, Kyle W. Doerksen, Jodene R. Eldstrom, Saman Rezazadeh, David Fedida

Journal:

The Journal of Physiology

Year:

2005

Language:

english

File:

PDF, 557 KB

english, 2005

22

Mechanisms of cardiac potassium channel trafficking

David F. Steele, Jodene Eldstrom, David Fedida

Journal:

The Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 371 KB

english, 2007

23

Gating currents from a Kv3 subfamily potassium channel: charge movement and modification by BDS-II toxin

Zhuren Wang, Brian Robertson, David Fedida

Journal:

The Journal of Physiology

Year:

2007

Language:

english

File:

PDF, 642 KB

english, 2007

24

Internalized Kv1.5 traffics via Rab-dependent pathways

Alireza Dehghani Zadeh, Hongjian Xu, Matthew E. Loewen, Geoffrey P. Noble, David F. Steele, David Fedida

Journal:

The Journal of Physiology

Year:

2008

Language:

english

File:

PDF, 1.77 MB

english, 2008

25

Kif5b is an essential forward trafficking motor for the Kv1.5 cardiac potassium channel

Alireza Dehghani Zadeh, Yvonne Cheng, Hongjian Xu, Nathan Wong, Zhuren Wang, Charitha Goonasekara, David F. Steele, David Fedida

Journal:

The Journal of Physiology

Year:

2009

Language:

english

File:

PDF, 586 KB

english, 2009

26

Kinetic analysis of the effects of H+ or Ni2+ on Kv1.5 current shows that both ions enhance slow inactivation and induce resting inactivation

Yen May Cheng, David Fedida, Steven J. Kehl

Journal:

The Journal of Physiology

Year:

2010

Language:

english

File:

PDF, 942 KB

english, 2010

27

Charged drug interactions at the inner mouth of K+ channels: Information gained from gating current studies

Fred S.P. Chen, David Fedida

Journal:

Perspectives in Drug Discovery and Design

Year:

1999

Language:

english

File:

PDF, 208 KB

english, 1999

28

Synergistic inhibition of the maximum conductance of Kv1.5 channels by extracellular K+reduction and acidification

David Fedida, Shetuan Zhang, Daniel C. H. Kwan, Cyrus Eduljee, Steven J. Kehl

Journal:

Cell Biochemistry and Biophysics

Year:

2005

Language:

english

File:

PDF, 219 KB

english, 2005

29

Constitutive inactivation of the hKv1.5 mutant channel, H463G, in K+-free solutions at physiological pH

Shetuan Zhang, Cyrus Eduljee, Daniel C. H. Kwan, Steven J. Kehl, David Fedida

Journal:

Cell Biochemistry and Biophysics

Year:

2005

Language:

english

File:

PDF, 141 KB

english, 2005

30

External K+ relieves the block but not the gating shift caused by Zn2+ in human Kv1.5 potassium channels

Shetuan Zhang, Daniel C. H. Kwan, David Fedida, Steven J. Kehl

Journal:

The Journal of Physiology

Year:

2001

Language:

english

File:

PDF, 215 KB

english, 2001

31

Superoxide radical production by allopurinol and xanthine oxidase

Chiara Galbusera, Peter Orth, David Fedida, Thomas Spector

Journal:

Biochemical Pharmacology

Year:

2006

Language:

english

File:

PDF, 287 KB

english, 2006

32

A structural interpretation of voltage-gated potassium channel inactivation

Harley T. Kurata, David Fedida

Journal:

Progress in Biophysics and Molecular Biology

Year:

2006

Language:

english

File:

PDF, 598 KB

english, 2006

33

Gating of voltage-dependent potassium channels

David Fedida, John Christian Hesketh

Journal:

Progress in Biophysics and Molecular Biology

Year:

2001

Language:

english

File:

PDF, 364 KB

english, 2001

34

Propagation of damage-induced contractions in rat cardiac muscle

Barbara J.M. Mulder, David Fedida, Henk E.D.J. ter Keurs

Journal:

Journal of Molecular and Cellular Cardiology

Year:

1991

Language:

english

File:

PDF, 77 KB

english, 1991

35

A specific N-terminal residue in Kv1.5 is required for upregulation of the channel by SAP97

Rajesh Mathur, Woo-Sung Choi, Jodene Eldstrom, Zhuren Wang, Jason Kim, David F. Steele, David Fedida

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 354 KB

english, 2006

36

α-Actinin-2 couples to cardiac Kv1.5 channels, regulating current density and channel localization in HEK cells

Neil D Maruoka, David F Steele, Billie P.-Y Au, Pauline Dan, Xue Zhang, Ed D.W Moore, David Fedida

Journal:

Year:

2000

Language:

english

File:

PDF, 507 KB

english, 2000

37

N-terminal PDZ-binding domain in Kv1 potassium channels

Jodene Eldstrom, Kyle W Doerksen, David F Steele, David Fedida

Journal:

Year:

2002

Language:

english

File:

PDF, 299 KB

english, 2002

38

SAP97 increases Kv1.5 currents through an indirect N-terminal mechanism

Jodene Eldstrom, Woo Sung Choi, David F Steele, David Fedida

Journal:

Year:

2003

Language:

english

File:

PDF, 329 KB

english, 2003

39

Localization of Kv1.5 channels in rat and canine myocyte sarcolemma

Jodene Eldstrom, David R. Van Wagoner, Edwin D. Moore, David Fedida

Journal:

Year:

2006

Language:

english

File:

PDF, 875 KB

english, 2006

40

A High-Na+ Conduction State during Recovery from Inactivation in the K+ Channel Kv1.5

Wang, Zhuren, Hesketh, J. Christian, Fedida, David

Journal:

Biophysical Journal

Year:

2000

Language:

english

File:

PDF, 299 KB

english, 2000

41

Modulation of Kv1.5 Potassium Channel Gating by Extracellular Zinc

Zhang, Shetuan, Kehl, Steven J., Fedida, David

Journal:

Biophysical Journal

Year:

2001

Language:

english

File:

PDF, 266 KB

english, 2001

42

Gating Charge Immobilization Caused by the Transition between Inactivated States in the Kv1.5 Channel

Wang, Zhuren, Fedida, David

Journal:

Biophysical Journal

Year:

2001

Language:

english

File:

PDF, 306 KB

english, 2001

43

The External K+ Concentration and Mutations in the Outer Pore Mouth Affect the Inhibition of Kv1.5 Current by Ni2+

Kwan, Daniel C.H., Eduljee, Cyrus, Lee, Logan, Zhang, Shetuan, Fedida, David, Kehl, Steven J.

Journal:

Biophysical Journal

Year:

2004

Language:

english

File:

PDF, 253 KB

english, 2004

44

KvLQT1's S3 involvement in LQTS

Loewen, Matthew E., Eldstrom, Jodene, Degenhardt, Amanda M., Xu, Hongjian, Fedida, David

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 42 KB

english, 2009

45

Voltage-dependent Fluorescence Associated with Native-Cysteine Residues in hERG channels

Fougere, Robert R., Xu, HongJian, Rezazadeh, Saman, Vaid, Moni, Fedida, David

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 130 KB

english, 2009

46

Modeling of Binding of the Anti-Arrhythmic Compound Vernakalant to Kv1.5

Eldstrom, Jodene, Fedida, David, Xu, Hongjian

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 42 KB

english, 2009

47

Blockade of Permeation by Potassium but Normal Gating of the G628S Nonconducting hERG Channel Mutant

Es-Salah-Lamoureux, Zeineb, Xiong, Ping Yu, Goodchild, Samuel J., Ahern, Christopher A., Fedida, David

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 816 KB

english, 2011

48

Single Channel Analysis Reveals Different Modes of Kv1.5 Gating Behavior Regulated by Changes of External pH

Kwan, Daniel C.H., Fedida, David, Kehl, Steven J.

Journal:

Biophysical Journal

Year:

2006

Language:

english

File:

PDF, 203 KB

english, 2006

49

An Activation Gating Switch in Kv1.2 Is Localized to a Threonine Residue in the S2-S3 Linker

Rezazadeh, Saman, Kurata, Harley T., Claydon, Thomas W., Kehl, Steven J., Fedida, David

Journal:

Biophysical Journal

Year:

2007

Language:

english

File:

PDF, 845 KB

english, 2007

50

External Ba2+ Block of Human Kv1.5 at Neutral and Acidic pH: Evidence for Ho+-Induced Constriction of the Outer Pore Mouth at Rest

Cheng, Y. May, Fedida, David, Kehl, Steven J.

Journal:

Biophysical Journal

Year:

2008

Language:

english

File:

PDF, 225 KB

english, 2008